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Medicine Research ›› 2018, Vol. 2 ›› Issue (4): 190001-.DOI: 10.21127/yaoyimr20190001

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Progress in the Relationship between Gut Microbiota and Type 2 Diabetes Mellitus

Ye Jiaa, Wenhui Wua, b, c, *   

  1. a College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China;
    b Shanghai Engineering Research Center of Aquatic-Product Processing & Preservation, Shanghai 201306, China;
    c National Experimental Teaching Demonstration Center for Food Science and Engineering,Shanghai Ocean University, Shanghai 201306, China
  • Received:2019-01-01 Revised:2019-02-14 Online:2018-12-20 Published:2019-03-04
  • Contact: Email: whwu@shou.edu.cn (W. W.)

Abstract: As one kind of normal metabolic disease, diabetes' development is associated with insanity, dietes, environment gut microbiota, and so on. Gut microbiota recognize and monitor the development of diabetes by short chain fatty acids, low grade inflammatory, and level of short chain fatty acids. Dietes, obesity, exercise and extreme environment can also influence the number and diversity of gut microbiota. Probiotics, prebiotics, antibiotic and fecal microbiota transplantation in turn contribute to the betterment of diabetes. In this paper, we summarize the relationship between gut microbiota and type 2 diabetes and new ideas based on gut microbiota for the treatment of diabetes, providing a reference for clinical prevention and treatment of type 2 diabetes.

Key words: type 2 diabetes, gut microbiota, probiotics, fecal microbiota transplantation

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