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Medicine Research ›› 2017, Vol. 1 ›› Issue (2): 35-37.DOI: 10.21127/yaoyimr20170010

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Activities of Naturally Occurring Alkaloids Bulleyaconitine A

Shiyang Zhaia,Wenjing Zhoua,Yifan Xua,Xiaosu Wanga,Xiao Yea,Shuyue Wanga,Wenhui Wua,Ruihua Guoabcde*   

  1. a College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China
    b Shanghai Engineering Research Center of Aquatic-Product Processing & Preservation, Shanghai 201306, China
    c National Experimental Teaching Demonstration Center for Food Science and Engineering (Shanghai Ocean University), Shanghai 201306, China
    d Laboratory of Quality and Safety Risk Assessment for Aquatic Product on Storage and Preservation (Shanghai), Ministry of Agriculture, Shanghai 201306, China
    e Quality Supervision, Inspection and Testing Center for Cold Storage and Refrigeration Equipment, Ministry of Agriculture, Shanghai 201306, China
  • Received:2017-09-29 Accepted:2017-10-18 Online:2017-09-08 Published:2017-12-07
  • Contact: Shiyang Zhai,Wenjing Zhou,Ruihua Guo

Abstract:

Bulleyaconitine A, a C19-diterpenoid alkaloid extracted from Aconitum bulleyanum Diels, showed various bioactivities, including anti-inflammatory, antinociceptivity, immunomodulatory effects as well as some toxicities. This paper reviewed the bioactivities of Bulleyaconitine A and the relevant mechanisms, toxicities, as well as the metabolism.

 

Key words: bulleyaconitine A, antinociceptivity, anti-inflammatory, immunomodulatory effects, toxicities

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