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Cover Illustration
2018, Vol.2  No.1
The cover picture shows the forms and structures of phlorotannins in different brown algae. The progress in bioactivities of phlorotannins was summarized. More details are discussed in the article by Wu et al. on page 180001.

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  • Table of Content
      25 March 2018, Volume 2 Issue 1 Previous Issue    Next Issue
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    Contents: Med. Res. 1/2018
    Medicine Research. 2018, 2 (1): 189001.  
    Abstract   PDF (438KB) ( )
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    Plant-Derived Kavalactones and Their Bioactivities
    Nenling Zhang, Linjing Wu, Xiang Liu, Xiangchun Shen
    Medicine Research. 2018, 2 (1): 170019.   DOI: 10.21127/yaoyimr20170019
    Abstract   HTML   PDF (721KB) ( )

    Kavalactones, mainly found in Piper methysticum, are a class of lactone compounds usually with an arylethylene-pyrone skeleton. Till now, fifty-one kavalactones have been isolated from the genera Piper, Alpinia, Amomum, Polygala, Goniothalamus, and Dumortiera. The bioactivities of six kavalactones, kawain, 7,8-dihydro- kawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyagonin, have been studied extensively. This review aims to give an overview of kavalactones in the plants and their various bioactivities.

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    Progress in Bioactivities of Phlorotannins from Sargassumi
    Jiaoyang Li, Yuxin Wang, Ruihua Guo, Bin Bao, Wenhui Wu
    Medicine Research. 2018, 2 (1): 180001.   DOI: 10.21127/yaoyimr20180001
    Abstract   HTML   PDF (490KB) ( )

    Bioactive components of marine species have received great attention in recent years, especially phlorotannins isolated from brown algae. This paper summarized progress in the structures and bioactivities of phlorotannins including antibacterial, antioxidant, anticoagulant, anti-diabetic, anti-hypertensive, inhibiting HIV, anti-tumor, anti-allergic, anti-inflammatory, defense activity, and deodorant activities.

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    Progress in Chemical Constituents and Pharmacological Effects of Lindera glauca
    Jianchen Liu, Chunyan Du, Yanan Li, Shiman Zuo, Rui Tan, Hezhong Jiang
    Medicine Research. 2018, 2 (1): 180003.   DOI: 10.21127/yaoyimr20180003
    Abstract   HTML   PDF (436KB) ( )

    Lindera glauca is a folk medicine with rich resources in China. Previous phytochemical studies on L. glauca have resulted in the isolation and identification of the main chemical constituents such as alkaloids, sitosterol, flavonoids, sesquiterpenes, and lignans, as well as essential oil, with antimicrobial, antitumor activity and other pharmacological effects. In this paper, the chemical compositions and pharmacological effects of L. glauca were summaried.

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    Recent Advances on anti-MRSA Natural Products Derived from Plants
    Jing Guo, Xiaoyu Su, Tianfang Ma, Jifeng Liu
    Medicine Research. 2018, 2 (1): 170018.   DOI: 10.21127/yaoyimr20170018
    Abstract   HTML   PDF (702KB) ( )

    Methicillin-resistant Staphylococcus aureus (MRSA) is a multi-drug resistant pathogenic bacteria, which has seriously threatened human health for a long time. Therefore, there is an urgent and unmet demand for new types of antibiotics. In response to the antibiotic resistance, many researchers have studied natural products derived from plant for alternative antibiotics and therapies. In this review, we summarized recent advances on anti-MRSA natural products from plants and their potential antibacterial effect against MRSA as potential anti-MRSA agents since 2007.

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    Natural Products Phenols as Novel Antithrombotic Agents
    Wenjing Zhou, Ruihua Guo
    Medicine Research. 2018, 2 (1): 180002.   DOI: 10.21127/yaoyimr20180002
    Abstract   HTML   PDF (217KB) ( )

    Thrombosis owns the highest incidence, and it is a serious threat to human health. Currently, the clinical antithrombotic drugs suffer from several drawbacks, causing allergic reactions or complications, etc. In recent years, small-molecule compounds isolated from natural products with antithrombotic activities in the field drug research on thrombus disease. In this review, we will focus on representative naturally occurring small molecule phenols with antithrombotic potency and potential for future therapeutic regimens to combat thrombosis disease.

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