Natural Products Phenols as Novel Antithrombotic Agents

doi:10.21127/yaoyimr20180002

Medicine Research ›› 2018, Vol. 2 ›› Issue (1): 180002-4.DOI: 10.21127/yaoyimr20180002

所属专题： Phytomedicine

Natural Products Phenols as Novel Antithrombotic Agents

^a College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China
^b Shanghai Engineering Research Center of Aquatic-Product Processing & Preservation, Shanghai 201306, China;
^c National Experimental Teaching Demonstration Center for Food Science and Engineering, Shanghai Ocean University, Shanghai 201306, China

收稿日期:2018-03-08 接受日期:2018-03-22 出版日期:2018-03-25 发布日期:2018-03-25

Natural Products Phenols as Novel Antithrombotic Agents

Wenjing Zhou^a, Ruihua Guo*^,a,^b,^c

^a College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China
^b Shanghai Engineering Research Center of Aquatic-Product Processing & Preservation, Shanghai 201306, China;
^c National Experimental Teaching Demonstration Center for Food Science and Engineering, Shanghai Ocean University, Shanghai 201306, China

Received:2018-03-08 Accepted:2018-03-22 Online:2018-03-25 Published:2018-03-25
Contact: Ruihua Guo

摘要/Abstract

Abstract:

Thrombosis owns the highest incidence, and it is a serious threat to human health. Currently, the clinical antithrombotic drugs suffer from several drawbacks, causing allergic reactions or complications, etc. In recent years, small-molecule compounds isolated from natural products with antithrombotic activities in the field drug research on thrombus disease. In this review, we will focus on representative naturally occurring small molecule phenols with antithrombotic potency and potential for future therapeutic regimens to combat thrombosis disease.

Key words: phenols, thrombosis, antithrombotic activities, natural products, aglycon

Wenjing Zhou, Ruihua Guo. Natural Products Phenols as Novel Antithrombotic Agents[J]. Medicine Research, 2018, 2(1): 180002-4.

参考文献

1	Nicholson, C. D.; Lensing, A. W. Expert Opin. Investig. Drugs 2001, 10, 785.
2	Lee Y. K.; Player, M. R. Med. Res. Rev. 2011, 31, 202.
3	Quinlan, D. J.; Eriksson, B. I.Best Pract. Res. Clin. Haematol. 2013, 26, 171.
4	Wei, X.; Yin, R. X.; Cardiology, D. O.Med. Recapitulate 2014, 20, 4520.
5	Xavier, A. R.; Siddiqui, A. M.; Kirmani, J. F.; Hanel, R. A.; Yahia, A. M.; Qureshi, A. I.CNS Drugs 2003, 17, 213.
6	Gross, P. L.; Weitz, J. I.Clin. Pharmacol. Ther. 2009, 86, 139.
7	Johannes, R.; Katus, H. A.Expert Opin. Investig. Drugs 2003, 12, 781.
8	Hsieh F.; Hsu C.; Huang H.; Shiau C. FEBS J.2005, 272, 407.
9	Balasubramaniam K.; Viswanathan G. N.; Marshall S. M.; Zaman, A. G. Cardiol. Res. Pract. 2012, 2012, 1.
10	Lees, K. R.; Bluhmki, E.; Kummer, R. V.; Brott, T. G.; Toni, D.; Grotta, J. C.; Albers, G. W.; Kaste, M.; Marler, J. R.; Hamilton, S. A.Lancet 2010, 375, 1695.
11	Peter, S.; Wardlaw, J. M.; Lindley, R. I.; Martin, D.; Geoff, C.; Gordon, M.; Karen, I.; Graham, V.; Anna, C.; Adam, K.Lancet 2012, 379, 2352.
12	Wardlaw, J. M.; Murray, V.; Berge, E.; Zoppo, G.; Sandercock, P.; Lindley, R. L.; Cohen, G.Lancet 2012, 379, 2364.
13	Guo R. H.; Zhang Y. T.; Duan D.; Fu Q.; Zhang X. Y.; Yu X. W.; Wang. S. J.; Bao B.; Wu, W. H. Chin. J. Chem. 2016, 34, 1194.
14	Wang G.; Wu W. H.; Zhu Q. G.; Fu S. Q.; Wang X. Y.; Hong S. T.; Guo R. H.; Bao, B. Chin. J. Chem. 2015, 33, 1089.
15	Guo R. H.; Duan D.; Zhang Y. T.; Fang Y. W.; Wu, W. H. Med. Res.2017, 1, 12.
16	Friederich, P. W.; Levi, M.; Biemond, B. J.; Charlton, P.; Templeton, D.; Zonneveld, A. J., Van; Bevan, P.; Pannekoek, H.; Cate, J. W.Circulation 1997, 96, 916.
17	Qiao J. X.; Wang T. C.; Réjean R.; Carl T.; Alexandre L. H.; Schumacher W. A.; Spronk S. A.; Sheldon H.; Gilles B.; John, L. J. Med. Chem. 2013, 56, 9275.
18	Massimo, C.; Savitri, K.; Das, C. M.; Reuben, J. M.; William, S.; Jamileh, N.; Frederick, B.; Gascoyne, P. R.Circ. Res. 2012, 111, 920.
19	Louisa, D.; Sim, D. S.; Dilks, J. R.; Price, B.; Sarah, B.; Denker, B. M.; Georgios, K.; Athan, K.; Robert, F.Proc. Natl. Acad. Sci. 2011, 108, 2951.
20	Bullingham A.; Strunin, L. Brit. J. Anaesth. 2009, 339, 622.
21	Abboud M.; Needle S.; Burns-Kurtis C.; Valocik R. P.; Amour A.; Chan C.; Brown D.; Chaudry L.; Zhou P.; Patikis, A. J. Cardiovasc. Pharm. 2008, 52, 66.
22	Eriksson B. I.; Dahl O. E.; Lassen M. R.; Ward D. P.; Rothlein R.; Davis G.; Turpie, A. G. G. J. Throm. Haemost. 2008, 6, 457.
23	Kolesnikov A.; Rai R.; Mordenti J.; Liu L.; Torkelson S.; Shrader W.; Leahy E.; Hu H.; Gjerstad E.; Janc, J. Bioorg. Med. Chem. Lett. 2006, 16, 2243.
24	Srivastava S.; Goswami L. N.; Dikshit, D. K. Med. Res. Rev. 2005, 25, 66.
25	Rai R.; Kolesnikov A.; Yong L.; Young W. B.; Leahy E.; Sprengeler P. A.; Verner E.; Shrader W. D.; Burgess H. J.; Sangalang, J. C. Bioorg. Med. Chem. Lett. 2001, 11, 1797.
26	Grover J. K.; Yadav S.; Vats V. J. Ethnopharmacol. 2002, 81, 81.
27	Hansen E.; Andersen, J. H. Curr. Pharm. Biotechnol. 2015, 17, 71.
28	Orlikova B.; Legrand N.; Panning J.; Dicato M.; Diederich, M. Cancer Treat. Res. 2014, 159, 123.
29	Sharma S. B.; Gupta, R. Mini-Rev. Med. Chem. 2015, 15, 52.
30	Tian L.; Teng X.; Zhong C. Gen. Chem. 2015, 1, 22.
31	Bravo L. Nutr. Rev. 1998, 56, 317.
32	Das M.; Khan W. A.; Asokan P.; Bickers D. R.; Mukhtar H. Cancer Res. 1987, 47, 767.
33	Pawlaczyk I.; Czerchawski L.; Kuliczkowski W.; Karolko B.; Pilecki W.; Witkiewicz W.; Gancarz R. Thromb. Res. 2011, 127, 328.
34	Rocca G. D.; Pugliese F.; Antonini M.; Coccia C.; Pompei L.; Venuta F.; Rendina E.A.; Ricci, C. J. Nat. Prod. 1997, 60, 1082.
35	Szewczuk L. M.; Penning, T. M. J. Nat. Prod. 2004, 67, 1777.
36	Pace A. C. R.; Hahn, S.; Diamandis, E. P.; Soleas, G.; Goldberg, D. M.Clin. Chim. Acta 1995, 235, 207.
37	Tsuchiya H.; Tanaka T.; Nagayama M.; Oyama M.; Iinuma, M. Nat. Prod. Commun. 2008, 3, 809.
38	Ito, J.; Niwa, M.Tetrahedron 1996, 52, 9991.
39	Li, W. W.; Ding, L. S.; Li, B. G.; Chen, Y. Z.Phytochemistry 1996, 42, 1163.
40	Kawabata, J.; Mishima, M.; Kurihara, H.; Mizutani, J.Phytochemistry 1995, 40, 1507.
41	Ito, J.; Gobaru, K.; Shimamura, T.; Niwa, M.; Takaya, Y.; Oshima, Y.Tetrahedron 1998, 54, 6651.
42	Yu L. H.; Wei J. T.; Chien C. S.; Chien, C. C. J. Nat. Prod. 2005, 68, 217.
43	Yoshida T.; Chen L.; Shingu T.; Okuda, T. Chem. Pharm. Bull. 1988, 36, 2940.
44	Okuda, T.; Yoshida, T.; Ashida, M.; Yazaki, K.J. Chem. Soc. Perkin Trans. 1983, 1765.
45	Nonaka, G. I.; Sakai, T.; Tanaka, T.; Mihashi, K.; Nishioka, I.Pharm. Bull. 1990, 38, 2151.
46	Lee, S. H.; Tanaka, T.; Nonaka, G. I.; Nishioka, I.Phytochemisry 1990, 29, 3621.
47	Dong H.; Chen S. X.; Kini R. M.; Xu, H. X. J. Nat. Prod. 1998, 61, 1356.
48	Jia T.; Wei D. Y.; Lin C.; Fang J. I.; Chao Z. X.; Qiang, S. Z. J. Kunming Med. Univ. 2009, 30, 14.
49	Shen Z. Q.; Chen P.; Shen J. Q.; Dong Z. J.; Liu, J. K. Nat. Prod. Res. Dev. 2003, 15, 441.
50	Dong S. X.; Kini R. M.; Xu H. X.; Dong H.; Chen S. X.; Xu, H. X. J. Nat. Prod. 1998, 61, 1356.
51	Ouyang X.; Takahashi K.; Komatsu K.; Nakamura N.; Hattori M.; Baba A.; Azuma, J. Jap. J. Pharm. 2002, 87, 289.
52	Wang X.; Morrisnatschke S. L.; Lee, K. H. Med. Res. Rev. 2007, 27, 133.
53	Lian N. L.; Rui T.; Wei, M. C. Planta Med. 1984, 50, 227.
54	Fan, H. Y.; Fu, F. H.; Yang, M. Y.; Xu, H.; Zhang, A. H.; Liu, K.Thromb. Res. 2010, 126, 17.
55	Ren W. J.; Kit M. L.; Po M. H.; Mak T. C. W.; Kam S. W.; Kwok, P. F. Curr. Med. Chem. 2005, 12, 237.
56	Zou, Z. W.Acta Pharm. Sinica 1993, 28, 241.
57	Neve J.; Leone P. A.; Carroll A. R.; Moni R. W.; Paczkowski N. J.; Pierens G. B.; Rquist P.; Deinum J.; Ehnebom J.; Inghardt, T. J. Nat. Prod. 1999, 62, 324.
58	Kozuka, M.; Sawada, T.; Kasahara, F.; Mizuta, E.; Amano, T.; Komiya, T.; Goto, M.Chem. Pharm. Bull. 1982, 30, 1952.
59	Cheng Q.; Snyder, J. K. J. Org. Chem. 1988, 53, 4562.
60	Kang, J.; Cabral, C.; Kushner, L.; Salzman, E. W.Blood 1994, 57, 1271.
61	Matsunaga K.; Shibuya M.; Ohizumi, Y. J. Nat. Prod. 1995, 58, 138.
62	Mei I. C.; Jing R. W.; Jih P. W.; Che M. T.; Chun, N. L. Planta Med. 2002, 68, 25.

Natural Products Phenols as Novel Antithrombotic Agents

Natural Products Phenols as Novel Antithrombotic Agents

RichHTML

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 0

编辑推荐

Metrics