Triterpenes from the genus Ficus and Their Bioactivities

doi:10.21127/yaoyimr20190004

Medicine Research ›› 2019, Vol. 3 ›› Issue (1): 190004-.DOI: 10.21127/yaoyimr20190004

收稿日期:2019-04-30 出版日期:2019-03-20 发布日期:2019-07-15
通讯作者: 2019-5-3

Triterpenes from the genus Ficus and Their Bioactivities

Qinru Zhou, Na Mao, Yan Chen, Shiquan Gan, Linjing Wu, Xiangchun Shen^*, Nenling Zhang^*

Department of Natural Medicinal Chemistry (State Key Laboratory of Functions and Applications of Medicinal Plants, High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province, High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Drug Ability, Union Key Laboratory of Guiyang City-Guizhou Medical University, Key Laboratory of Optimal Utilization of Natural Medicine Resources), School of Pharmaceutical Sciences, Guizhou Medical University,Guiyang, Guizhou 550025, China

Received:2019-04-30 Online:2019-03-20 Published:2019-07-15
Supported by:
Email: shenxiangchun@126.com (X. S.), nenlingzhang@foxmail.com (N. Z.)

摘要/Abstract

Abstract: Triterpenoids exist commonly in the genus Ficus. Till now, ninety-seven triterpenes have been isolated from the genus Ficus. The bioactivities of five triterpenes including maslinic acid, oleanolic acid, lupeol, betulinic acid and ursolic acid have been studied extensively. Herein, we provide an overview of triterpenes in the genus Ficus and their various bioactivities.

Key words: Ficus, triterpenoids, oleanolic acid, bioactivities

. [J]. Medicine Research, 2019, 3(1): 190004-.

Qinru Zhou, Na Mao, Yan Chen, Shiquan Gan, Linjing Wu, Xiangchun Shen, Nenling Zhang. Triterpenes from the genus Ficus and Their Bioactivities[J]. Medicine Research, 2019, 3(1): 190004-.

参考文献

[1] Delectis Florae Reipublicae Popularis Sinicae Agendae A-cademiae Sinicae Edita, Florae Reipublicae Popularis Sinicae, Vol. 23, Science Press, Beijing, China, 1998.
[2] Jiangsu Institute of Botany, Institute of Materia Medica Chinese Academy of Medical Sciences, Kunming Institute of Botany Chinese Academy of Sciences, XinHua BenCaoGangYao (II), Shanghai Science and Technology Press, Shanghai, China, 1991.
[3] Chiang Y. M.; Kuo Y. H.[J]. Nat. Prod. 2000, 63, 898.
[4] Chiang Y.M.; Chang J. Y.; Kuo C. C.; Chang C. Y.; Kuo Y. H. Phytochemistry 2005, 66, 495.
[5] Chiang Y. M.; Kuo Y. H.[J]. Nat. Prod. 2001, 64, 436.
[6] Chiang Y. M.; Su J. K.; Liu Y.H.; Kuo Y. H. Chem. Pharm. Bull. 2001, 49, 581.
[7] Kuo Y. H.; Chiang Y. M. Chem. Pharm. Bull. 1999, 47, 498.
[8] Kuo Y. H.; Li Y. C.[J]. Chin. Chem. Soc. 1997, 44, 321.
[9] Higa M.; Yogi S.; Hokama K. Bull. Coll. Sci. Univer.Ryukyus. 1987, 44, 75.
[10] Kitajima J.; Arai M.; Tanaka Y. Chem. Pharm. Bull. 1994, 42, 608.
[11] Kitajima J.; Kimizuka K.; Tanaka Y. Chem. Pharm. Bull. 1998, 46, 1408.
[12] Kitajima J.; Kimizuka K.; Tanaka Y. Chem. Pharm. Bull. 1999, 47, 1138.
[13] Pistelli L.; Chiellini E. E.; Morelli I. Biochem. Syst. Ecol. 2000, 28, 287.
[14] Ragasa C. Y.; Juan E.; Rideout J. A.[J]. Asian. Nat. Prod. Res. 1999, 1, 269.
[15] Kitajima J.; Kimizuka K.; Arai M.; Tanaka Y. Chem. Pharm. Bull. 1998, 46, 1647.
[16] Tuyen N. V.; Kima D. S.H. L.; Fong, H. S.; Soejarto, D. D.; Khanh, T. C.; Tri, M. V.; Xuan L. T. Phytochemistry 1998, 50, 467.
[17] Awolola G. V.; Chenia H.; Baijnath H.; Koorbanally N. A. Rev. Bras. Farmacogn. 2017, 27, 599.
[18] Jain R.; Rawat S.; Jain S. C.[J]. Pharm. Res. 2013, 6, 615.
[19] Kuo P. C.; Chiu C. C.; Shi L. S.; Li C. Y.; Wu S. J.; Damu A. G.; Wu P.L.; Kuo C. S.; Wu T. S.[J]. Chin. Chem. Soc. 2002, 49, 113.
[20] Ahmed W.;Khan A. Q.; Malik, A. Planta Med. 1988, 54, 481.
[21] Ramadan M. A.; Ahmad A. S.; Nafady A. M.; Mansour A. I. Nat. Prod. Res. 2009, 23, 1218.
[22] Parveen M.; Ghalib R. M.; Mehdi S. H.; Mattu R. U.H.; Ali, M. [J]. Saudi. Chem. Soc. 2009, 13, 287.
[23] Mbosso E. J.T.; Nguedia, J. C. A.; Meyer, F.; Lenta, B. N.; Ngouela, S.; Lallemand, B.; Mathieu, V.; Antwerpen, P. V.; Njunda, A. L.; Adiogo, D.; Tsamo, E.; Looze, Y.; Kiss R.; Wintjens, R. Phytochemistry 2012, 83, 95.
[24] Wang Y. L.; Liang H.; Zhang Q. Y.; Cheng W.; Yi, S. R. Biochem. Syst. Ecol. 2014, 57, 210.
[25] Yessoufou K.; Elansary H. O.; Mahmoud E. A.; Skalicka-Woźniak, K. Ind. Crop. Prod. 2015, 74, 752.
[26] Lopes D.; Villela C. T.; Kaplan M. A. C.; Carauta, J. P. P. Phytochemistry 1993, 34, 279.
[27] Hsia T. C.; Liu W. H.; Qiu W. W.; Luo J.; Yin M. C. Molecules 2014, 19, 19892.
[28] Mu D. W.; Guo H. Q.; Zhou G. B.; Li J. Y.; Su B. Int.[J]. Clin. Exp. Pathol. 2015, 8, 13864.
[29] Weber D.; Zhang M.; Zhuang P.; Zhang, Y; Wheat J.; Currie G.; Al-Eisawi, Z. Sage. Open. Med. 2014, 2, 2050312114551974.
[30] Narender T.; Khaliq T.; Singh A. B.; Joshi M. D.; Mishra P.; Chaturvedi J. P.; Srivastava A. K.; Maurya R.; Agarwal, S. C. Eur. [J]. Med. Chem. 2009, 44, 1215.
[31] Ko B.S.; Kang, S.; Moon, B. R.; Ryuk J. A.; Park, S. Evid-Based Compl. Alt. 2016, 11, 1.
[32] Zhang J.; Lu X.; Fan Q.; Xu L.; Li L.; Yue Y.; Xu Y.; Su Y.; Zhang D.; Wang, L. Plos One 2015, 10, e0117400.
[33] Kim S. J.; Cho H. I.; Kim S. J.; Kim J. S.; Kwak, J. H; Lee, D. U.; Lee S. K.; Lee, S. M. [J]. Nat. Prod. 2014, 77, 2383.
[34] Badshah H.; Ali T.; Rehman, S. U; Amin, F. U.; Ullah F.; Kim T. H.; Kim, M. O. [J]. Neuroimmune. Pharm. 2015, 11, 48.
[35] Qian Y.; Huang M.; Guan T.; Chen L.; Cao L.; Han X. J.; Huang L.; Tang X.; Li Y. ; Sun, H. Eur. [J]. Pharmacol. 2015, 764, 298.
[36] Park S. N.;Ahn S. J.; Kook, J. K. Braz. [J]. Microbiol. 2015, 46, 613.
[37] Jamkhande P. G.;Pathan S. K.; Wadher, S. J. Int. [J]. Mycoba. 2016, 5, 417.
[38] Lin C. K.; Tseng C.K.; Chen K. H.; Wu S. H.; Liaw C. C.; Lee, J. C. Brit. [J]. Pharmacol. 2015, 172, 4481.
[39] Cao T. W.; Geng C. A.; Jiang F. Q.; Ma Y. B.; He K.; Zhou N. J.; Zhang X. M.; Zhou J.; Chen, J. [J]. Fitoterapia 2013, 89, 175.
[40] Saha B.; Yamamoto E. S.; Campos B. L.S.; Jesus, J. A.; Laurenti, M. D.; Ribeiro, S. P.; Kallás, E. G.; Rafael-Fernandes, M.; Santos-Gomes, G.; Silva, M. S.; Sessa, D. P.; Lago, J. H. G.; Levy D.; Passero, L. F. D. Plos One 2015, 10, e0144946.
[41] Esposito F.; Sanna C.; Del Vecchio, C.; Cannas, V.; Venditti, A.; Corona, A.; Bianco, A.; Serrilli, A. M.; Guarcini, L.; Parolin, C.; Ballero M.; Tramontano, E. Pathog. Dis. 2013, 68, 116.

Triterpenes from the genus Ficus and Their Bioactivities

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