Flavonoids, Phenylethanoids and Phenylpropanoids from Rhodiola rosea L. and Their Lipid-Lowering Activities on Receptor 5-HT2A

doi:10.21127/yaoyimr20200018

Medicine Research ›› 2020, Vol. 4 ›› Issue (4): 200018-200018.DOI: 10.21127/yaoyimr20200018

所属专题： Phytomedicine

Flavonoids, Phenylethanoids and Phenylpropanoids from Rhodiola rosea L. and Their Lipid-Lowering Activities on Receptor 5-HT_2A

Hao Wang,^a,b Ji-Lei Liang,^a Qing-Ming He,^a Guo-Hai Zhou,^a Cun-Fu Li,^a Ping-He Wei,^a and Hao-Yan Dong^*,a

^a Jiangsu Key Laboratory of Chiral Pharmaceuticals Biosynthesis, Taizhou University, Taizhou, Jiangsu 225300, China
^b DICP-CMC Innovation Institute of Medicine, Taizhou, Jiangsu 225300, China

收稿日期:2020-11-01 修回日期:2020-12-12 出版日期:2020-12-20 发布日期:2020-12-20
基金资助:

Flavonoids, Phenylethanoids and Phenylpropanoids from Rhodiola rosea L. and Their Lipid-Lowering Activities on Receptor 5-HT_2A

Hao Wang,^a,b Ji-Lei Liang,^a Qing-Ming He,^a Guo-Hai Zhou,^a Cun-Fu Li,^a Ping-He Wei,^a and Hao-Yan Dong^*,a

^a Jiangsu Key Laboratory of Chiral Pharmaceuticals Biosynthesis, Taizhou University, Taizhou, Jiangsu 225300, China
^b DICP-CMC Innovation Institute of Medicine, Taizhou, Jiangsu 225300, China

Received:2020-11-01 Revised:2020-12-12 Online:2020-12-20 Published:2020-12-20
Contact: donghaoyan2008@126.com (H. Y. D.)
Supported by:

摘要/Abstract

摘要：

关键词:

Abstract: Fifteen compounds, including 11 flavonoids, 2 phenylethanoids and 2 phenylpropanoids, were isolated from the roots of Rhodiola rosea L. Among them, quercetin (1) and quercetin-3-O-β-D-glucoside (2) were afforded from the genus Rhodiola for the first time. All isolates were evaluated for their agitating activities on receptor 5-HT_2A and four compounds (12—15) showed obvious agitating activities, which were probably the main lipid-lowering active components of R. rosea L.

Key words: flavonoids, phenylpropanoids, phenylethanoids, Rhodiola rosea, lipid-lowering activity, receptor 5-HT_2A

中图分类号:

Hao Wang, Ji-Lei Liang, Qing-Ming He, Guo-Hai Zhou, Cun-Fu Li, Ping-He Wei, and Hao-Yan Dong. Flavonoids, Phenylethanoids and Phenylpropanoids from Rhodiola rosea L. and Their Lipid-Lowering Activities on Receptor 5-HT_2A[J]. Medicine Research, 2020, 4(4): 200018-200018.

[1]	Zhao Wang, Filipe Olim, Jingjing Sun, Ana Rute Neves, Fátima Mendes, Helena Tomás, and Ruilong Sheng. Prodrug Systems (II): A Perspective of Polymer-Based Doxorubicin Prodrug Systems towards Chemotherapy[J]. Medicine Research, 2021, 5(1): 200023-200023.
[2]	. Contents: Med. Res. 4/2020 [J]. Medicine Research, 2020, 4(4): 0-0.
[3]	. [J]. Medicine Research, 2020, 4(1-2): 209001-209001.
[4]	. Contents: Med. Res. 3/2019[J]. Medicine Research, 2019, 3(4): 0-0.
[5]	. 2019 Nobel Prize in Physiology or Medicine[J]. Medicine Research, 2019, 3(4): 196002-.
[6]	Chaoyan Zhang. Chaoyan Zhang[J]. Medicine Research, 2019, 3(4): 198003-.
[7]	. Contents: Med. Res. 3/2019[J]. Medicine Research, 2019, 3(3): 0-.
[8]	Jun Zhu, Jiejun Cheng, Juan Zhou, Gang Huang, Dannong He. Surface Modification on Ultra High Molecular Weight Polyethylene Scaffold with Silk Fibroin[J]. Medicine Research, 2019, 3(2): 190006-.
[9]	Jingjuan Li, Fucai Ren, Jiangmiao Hu. Progress of Picrotoxane Type Alkaloids in Dendrobium[J]. Medicine Research, 2019, 3(2): 190007-.
[10]	. Xplorer Awards in Life Sciences[J]. Medicine Research, 2019, 3(2): 20196001-.
[11]	. Interview with Professor Nenling Zhang[J]. Medicine Research, 2019, 3(2): 198002-.
[12]	. Contents: Med. Res. 2/2019 [J]. Medicine Research, 2019, 3(2): 0-.
[13]	Medicine Research. Contents: Med. Res. 3/2018[J]. Medicine Research, 2018, 2(3): 0-0.
[14]	. [J]. Medicine Research, 2018, 2(2): 180005-.
[15]	. Contents: Med. Res. 2/2018[J]. Medicine Research, 2018, 2(2): 180000-.

Flavonoids, Phenylethanoids and Phenylpropanoids from Rhodiola rosea L. and Their Lipid-Lowering Activities on Receptor 5-HT_2A

Flavonoids, Phenylethanoids and Phenylpropanoids from Rhodiola rosea L. and Their Lipid-Lowering Activities on Receptor 5-HT_2A

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics