Loading...
Home
About the Journal
Editorial Board
Aims & Scope
Peer Review Policy
Subscription
Contact Us
Search Article
Adv Search
Early Edition
//
Current Issue
//
Archives
//
Most Read
//
Most Downloaded
//
Most Cited
Cover Illustration
2020, Vol.4 No.1-2
The cover picture
shows chemical constituents and pharmacological effects of Citrus
medica
L.
var. sarcodactylis
Swingle. More details are discussed in the article by Jiang
et al.
on page 190014.
Online ISSN 2521-8743
About the Journal
»
About Journal
»
Editorial Board
Authors
»
Online Submission
»
Guidelines for Authors
»
Download Templates
»
Copyright Agreement
Reviewers
»
Guidelines for Reviewers
»
Online Peer Review
»
Online Editor Work
Editorial Office
Virtual Special Issues
Table of Content
10 June 2020, Volume 4 Issue 1-2
Previous Issue
Next Issue
For Selected:
View Abstracts
Download Citations
EndNote
Reference Manager
ProCite
BibTeX
RefWorks
Toggle Thumbnails
Contents
Select
Contents: Med. Res. 1-2/2020
Medicine Research
Medicine Research. 2020,
4
(1-2): 209001.
Abstract
PDF
(317KB) (
)
Related Articles
|
Metrics
Perspective
Select
Prodrug Systems (I): Lipid-Based Doxorubicin Prodrugs and Their Nanodelivery Systems
Filipe Olim, Ana Rute Neves, Zhao Wang, Jingjing Sun, Helena Tomás, and Ruilong Sheng
Medicine Research. 2020,
4
(1-2): 200013. DOI: 10.21127/yaoyimr20200013
Abstract
PDF
(518KB) (
)
Using natural lipids to covalently connect with antitumor agents to construct lipid-based molecular prodrugs and their nanosystems is a promising research frontier for sustainable medicinal chemistry, nanobiotechnology and tumor chemotherapy. This paper reviewed recent progress of lipid-based doxorubicin (molecular) prodrugs and their nanodelivery systems, including lipid-doxorubicin prodrugs, stimuli-responsive lipid-doxorubicin prodrugs, and lipid-doxorubicin prodrug-based drug co-delivery nanosystems. Additionally, possible future research outlooks in this field were also discussed.
References
|
Related Articles
|
Metrics
Reports
Select
Augmented Reality in Drug Package: a Promising Strategy against Non-adherence in the Treatment of Tuberculosis
Dayse E. de Oliveira, Marcus V. N. de Souza, Wanise B. G. Barroso
Medicine Research. 2020,
4
(1-2): 200007. DOI: 10.21127/yaoyimr20200007
Abstract
PDF
(562KB) (
)
Augmented reality is a technology-based on an interaction between the virtual and real-world, mixing them and expanding their possibilities. This technology is currently used in the most varied areas of human knowledge. The use of augmented reality in drug package has excellent potential in several diseases and could be an indispensable tool, especially in diseases with low medication adherence. In this context, its application in tuberculosis treatment could be of great help, as this treatment presents two major issues: the long-term treatment time (six months) and its severe side effects resulting in its non-adherence to the treatment. In this article, we aim to address the problems related to tuberculosis treatment causing non-adherence by using augmented reality. Using a smartphone in the medicine packaging could gain valuable information making patients be aware of following the treatment until the end.
Related Articles
|
Metrics
Select
Renoprotective Effect of Sulphate Polysaccharide from Brown Algae on Ethylene Glycol-Induced Renal Damage in Rats
Hui Huang, Junwen Wang, Xueyan Li, Wenhui Wu, Kejin Shi, and Chaoyan Zhang
Medicine Research. 2020,
4
(1-2): 190010. DOI: 10.21127/yaoyimr20190010
Abstract
PDF
(751KB) (
)
The protective effect of the polysaccharides on ethylene glycol induced kidney impairment has been explored. Polysaccharides have been extracted from Sargassum graminifolium, which belongs to brown algae. Three different doses of polysaccharides were used for rats with kidney stones by ethylene glycol feeding. Then, urinary biochemistry parameters, renal function factors including blood urea nitrogen (BUN) and serum creatinine (Scr) levels were detected. Besides, interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) in kidney tissue were elevated, which belong to proinflammatory cytokines. Moreover, kidney histopathological sections were examined. The results illustrated that polysaccharides not only increased calcium level but also decreased oxalate, Scr, and BUN levels. In addition, the levels of IL-6 and TNF-α were reduced. Moreover, renal micro-scopic analysis showed polysaccharides treatment alleviated observably calcium oxalate deposits in the kidney tissue. The results indicated that the renoprotective mechanism of SGP may be attributed to suppression of inflammation, reducing the growth of urinary stones and improving kidney function in vivo, which explained SGP through multiple ways to protect kidney cells from damaging of hyperoxaluria rats.
References
|
Related Articles
|
Metrics
Minireviews
Select
Diterpenoids from the genus Illicium and Their Bioactivities
Yingying Fu, Junyan Chu, and Jifeng Liu
Medicine Research. 2020,
4
(1-2): 200005. DOI: 10.21127/yaoyimr20200005
Abstract
PDF
(540KB) (
)
Diterpenoids are important chemical constituents isolated from the genus
Illicium
, which possess many pharmacological effects such as anti-inflammatory, antiviral activities, cytotoxicity, and so on. Up to now, 68 diterpenoids have been isolated from the genus
Illicium
, and they are classified as abietane-type, pimarane-type and podocarpane-type. In this paper, the chemical constituents and bioactivities of the diterpenoids from the genus
Illicium
are reviewed.
References
|
Related Articles
|
Metrics
Select
Progress in Chemical Compositions and Pharmacological Activities of FlosPopuli
Junyan Chu, Yingying Fu, and Jifeng Liu
Medicine Research. 2020,
4
(1-2): 200006. DOI: 10.21127/yaoyimr20200006
Abstract
PDF
(790KB) (
)
FlosPopuli is a dry male inflorescence of Populus tomentosa., Populus canadensis. Some researches show that FlosPopuli contains rich flavonoids and phenolic glycosides, which have antibacterial, anti-inflammatory, anti-oxidant and anti-viral effects. In order to systematically understand the chemical compositions and biological activities of FlosPopuli and lay the foundation for subsequent research, this article reviews the two above aspects. Fifty-three kinds of flavonoids, phenol glycosides and others were isolated from FlosPopuli; moreover, their antibacterial, anti-inflammatory and hypolipidemic effects were investigated.
References
|
Related Articles
|
Metrics
Select
Progress in Chemical Constituents and Pharmacological Effects of Citrus
medica
L. var.
sarcodactylis
Swingle
Shuyu Xu, Yin Qu, Xinyu Liu, Yao Li, Jimin Liu, Hezhong Jiang
Medicine Research. 2020,
4
(1-2): 190014. DOI: 10.21127/yaoyimr20190014
Abstract
PDF
(580KB) (
)
Citrus medica
L. var. sarcodactylis Swingle is known as Foshou fruit that can be used as Chinese medicinal materials and has a health and longevity effect. In recent years, investigations about the chemical compounds of
Citrus medica
L. var.
sarcodactylis
Swingle have shown that its main compounds include flavonoids, essential oils, coumarins, and polysaccharides, with anti-inflammatory, antimicrobial, antioxidant activity, effect on the autonomic nervous system, and other pharmacological effects. In this paper, the chemical compositions and pharmacological effects of
Citrus medica
L. var.
sarcodactylis
Swingle are summarized.
Related Articles
|
Metrics
News
More
Journal Indexing
沪ICP备15041762号-3
Copyright © Medicine Research, All Rights Reserved.
Address: 425 East 76th Street, Apt 9E, New York, NY, 10021, United States