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Cover Illustration
2021, Vol.5  No.3-4
The cover picture shows that Paeonia is composed of P. suffruticosa Andr, P. labiflora, P. delavayi, P. rockii, etc. Monopenoids have been isolated in the genus, which can be divided into paeoniflorin type paeonisufrrone type, albiflorin type, paeoniflorone type, and paeoniflorgenone type. More details are discussed in the article by Xu et al. on page 210011.

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  • Table of Content
      20 September 2021, Volume 5 Issue 3-4 Previous Issue    Next Issue
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    Natural Products from the genus Daldinia and Their Bioactivities

    Jing Li, Luohao Li, Runqing Zhu, Vuanghao Lim, Qianqian Sun, and Lizhen Fang
    Medicine Research. 2021, 5 (3-4): 210005.   DOI: 10.21127/yaoyimr20210005
    Abstract   PDF (1005KB) ( )
    Genus Daldinia is a unique source of natural products, which possess many pharmacological effects such as antibacterial activity, cytotoxicity, antioxidant activity, α-glucosidase inhibitory activity, and so on. Recently, most studies of genus Daldinia were focused on D.eschscholzii, D.concentrica and D.sp. This paper covers nearly a decade of research on Daldinia, focusing on the chemical structures and related biological activities of the secondary metabolites produced.
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    Study on Chemical Constituents and Bioactivities from Eucalyptus globulus
    Shudan Zheng, Hui Fang, Jifeng Liu
    Medicine Research. 2021, 5 (3-4): 210007.   DOI: 10.21127/yaoyimr20210007
    Abstract   PDF (1222KB) ( )
    Eucalyptus globulus (E. globulus) is a tall timber tree of genus Eucalyptus (Myrtaceae), and it is mainly distributed in the southern and southwestern China. The dry fruits of E. globulus, called as ‘Yi-Kou-Zhong’ in Chinese, have been commonly used as a traditional Chinese medicine to treat in flammation, eczema, and influenza. Herein, we summarized the chemical constituents and bioactivities of the Eucalyptus globulus.
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    Progress in Chemical Constituents and Bioactivities of Perilla frutescens (L.) Britt
    Hui Fang, Shudan Zheng, Jifeng Liu
    Medicine Research. 2021, 5 (3-4): 210008.   DOI: 10.21127/yaoyimr20210008
    Abstract   PDF (744KB) ( )
    Perilla frutescens (L.) Britt is an annual herb of the genus Perilla in the labiaceae. Its leaves, stalks and fruits can be used as folk medicine. The chemical components in Perilla frutescens (L.) Britt can be divided into volatile oil, terpenoids, triterpenoids, steroids, glycosides, phenylpropanoids and phenolic acids, flavonoids and pigments, which have anti-allergy, antibacterial, hypolipidemia, antioxidation, antitumor, antitussive and antipyretic activities. In this paper, we reviewed research progress of chemical constituents and pharmacological effects of Perilla frutescens to provide new ideas for subsequent development of Perilla frutescens (L.) Britt.
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    Progress in Chemical Constituents and Pharmacological Effects of Lindera obtusiloba Bl
    Hong Zhou, Qingtian Gao, Jisong Mo, Jimin Liu, Na Pan, Chunyi Duan, Xin Chen , Hezhong Jiang
    Medicine Research. 2021, 5 (3-4): 210010.   DOI: 10.21127/yaoyimr20210010
    Abstract   PDF (672KB) ( )
    Lindera obtusiloba Bl belongs to the genus Lindera, which has a long history of medicinal use and a wide range of uses. It has many significant physiological activities such as improving blood circulation, treating inflammation and preventing liver injury. Investigations about the chemical compounds of L. obtusiloba have shown that its main compounds include butyrolactones, lignans, flavonoids, phytosterols, volatile oils and phenolic glycosides, with antibacterial, anti-inflammatory, cytotoxicity, anti-oxidation and anti-fibrosis activities. At present, there are few reports on its chemical constituents and physiological activities. Herein, we summarized the reported chemical constituents and physiological activities of L. obtusiloba and laid a foundation for further research.
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    Progress in Terpenes from Genus Paeonia
    Lei Sun, Chuihao Kong, Huan Zhao, Deling Wu, Fengqing Xu
    Medicine Research. 2021, 5 (3-4): 210011.   DOI: 10.21127/yaoyimr20210011
    Abstract   PDF (637KB) ( )
    Paeonia is the single genus of ca. 35 known species in the family Paeoniaceae. Up to now, more than 185 terpenes have been isolated from root/root cortex, flowers and seeds of the genus Paeonia. Researches had focused on the following species, such as P. lactiflora, P. suffruticosa Andr, P. veitchii, P. labiflora, P. delavayi, P. rockii, P. emodi, P. peregrina, and P. japonica. In this paper, the terpenes of Paeonia were reviewed, which may provide more useful information for further development on this genus.
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    Reports
    Pharmacist Intervention with Computer-Based Alert System and Assessment of Prescription Errors for Outpatient in a Chinese Tertiary Hospital
    Qing Shen, Yi-Meng Zhou, Jin Lv, Hua Yang, Yuan-yuan He, Yuan Bian, Yong Han
    Medicine Research. 2021, 5 (3-4): 210009.   DOI: 10.21127/yaoyimr20210009
    Abstract   PDF (639KB) ( )
    Qualified prescribing is fundamental for appropriate use of medicine. Pharmacist interventions potentially remind physicians to cope with this issue. This study aimed to report interventions implemented by pharmacists with real-time computer-based alert system and evaluate the prescription errors for outpatients in a Chinese tertiary hospital. This retrospective, non-comparative study was implemented with an analysis of data collected from October to December in 2018 involved all clinical specialty departments in the hospital. Alerts were generated and displayed on pharmacist screen while prescribing inappropriately, then pharmacists chose certain operation and offered recommendations according to the alerts. Outcomes such as category and acceptance rate of pharmacist recommendations, prescription error types, prevalence rate, severity level and monthly tendency were documented, categorized and analyzed. In our study, 2.3% of prescriptions generated alerts, and incidence of pharmacist interventions was 0.19%. 431 prescription errors were prevented, with the overall acceptance rate of interventions accounted for 29.7%. Dosage or frequency problems (n = 170, 39.5%), contraindications (n = 79, 18.3%) and improper duration of pharmacotherapy (n = 53, 12.3%) were the top three types of prescription errors. Monthly rate of errors decreased from 0.98 to 0.43 per 1000 prescriptions in the monitoring period. Pharmacist interventions with computer-based alert system were available for filtering part of invalid alerts and preventing prescription errors in our study.
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