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Medicine Research ›› 2017, Vol. 1 ›› Issue (1): 12-15.DOI: 10.21127/yaoyimr20170006

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Flavonnoids with Antithrombotic Activities: a Review

Guo Ruihuaac,Duan Donga,Zhang Yitinga,Fang Yiwenb*(),Wu Wenhuiac*()   

  1. a College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China
    b Department of Chemistry, Shantou University, Shantou, Guangdong 515063, China
    c Shanghai Engineering Research Center of Aquatic-Product Processing & Preservation, Shanghai 201306, China
  • Online:2017-08-08 Published:2017-08-04
  • Contact: Fang Yiwen,Wu Wenhui


Thrombus is a severe health problem all over the world, especially in developing countries. However, there is still no satisfactory antithrombotic therapeutic strategy. Currently, the clinical antithrombotic drugs suffer from several drawbacks such as high rate of bleedings and short half-life, causing allergic reactions or complications, etc. In recent years, small-molecule compounds isolated from natural products with antithrombotic activities become a hot issue in the field of drug research. In this review, we will focus on representative naturally occurring small molecule flavonoids with antithrombotic potency and potential for future therapeutic regimens to combat thrombosis disease.


Key words: thrombosis, small-molecule, antithrombotic activities, natural products, flavonoids

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