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Medicine Research ›› 2022, Vol. 6 ›› Issue (3-4): 220002-220002.DOI: 10.21127/yaoyimr20220002

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Recent Advances on Anticancer Effects and Molecular Mechanisms of Maslinic Acid

Jin Lia,b, Xiaomei Yanga,b, Wei Jianga,b, Qianqian Hua,b, Xuanjun Wang*,a,b, Huanhuan Xu*,a,b   

  1. aKey Laboratory of Pu-er Tea Science, Ministry of Education, Yunnan Agricultural University,Kunming, Yunnan 650201, China;
    bCollege of Science, Yunnan Agricultural University, Kunming, Yunnan 650201, China
  • Received:2022-02-21 Accepted:2022-03-06 Online:2022-12-20 Published:2023-02-24
  • Contact: Email: wangxuanjun@gmail.com (X. W.), xuhuan1017@163.com (H. X.)

Abstract: Cancer has become a serious public health concern that affects millions of individuals annually in the world. Surgical resection, chemotherapy and radiotherapy have been considered as the standard treatment strategies for different kinds of cancers. Among them, chemotherapeutic agents are usually used for the treatment of malignancies but toxic side effects and drug resistance limit their clinical efficacy. Natural compounds isolated from medicinal plants are excellent and reliable sources of new anticancer drugs. Maslinic acid is a naturally occurred pentacyclic triterpenoid with anticancer activities. This review mainly focuses on recent advances on anticancer effects and molecular mechanisms of maslinic acid and will hopefully provide valuable insights into clinical application of maslinic acid to the treatment of cancers.

Key words: maslinic acid, anticancer, mechanism, interaction target

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