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Medicine Research ›› 2020, Vol. 4 ›› Issue (3): 200008-.DOI: 10.21127/yaoyimr20200008

Special Issue: Drug Delivery

• Minireviews •     Next Articles

Progress in Percutaneous Penetration Enhancers from Traditional Chinese Medicines

Yingying Huang,a Jinyu Yi,a and Chaoyan Zhang*,a,b,c,d   

  1. a College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China
    b Shanghai Engineering Research Center of Aquatic-Product Processing & Preservation, Shanghai 201306, China
    c Laboratory of Quality and Safety Risk Assessment for Aquatic Product on Storage and Preservation (Shanghai), Ministry of Agriculture, Shanghai 201306, China
    d Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian, Liaoning 116034, China
  • Received:2020-05-21 Revised:2020-08-13 Online:2020-09-22 Published:2020-09-22
  • Contact: chyzhang@shou.edu.cn (C. Z.)
  • Supported by:

Abstract: Percutaneous penetration enhancers can regulate the transdermal absorption of drugs. Generally speaking, it can be divided into two categories: chemical synthesis and natural sources. Natural percutaneous penetration enhancers have the advantages of safety and mildness. This review summarizes the mechanism and characteristics of three kinds of percutaneous penetration enhancers and their combined application in transdermal drug delivery systems. The three different types of percutaneous penetration enhancers are fatty acids, alkaloids and terpenes. It is expected to provide considerations for the application research of percutaneous penetration enhancers rich in traditional Chinese medicines in transdermal drug delivery systems.


Key words: traditional Chinese medicines, percutaneous penetration enhancers, combined application

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