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Medicine Research ›› 2021, Vol. 5 ›› Issue (1): 200022-200022.DOI: 10.21127/yaoyimr20200022

Special Issue: Anticancer Agents

• Minireview • Previous Articles     Next Articles

Adverse Reactions and Resistance of Anticancer Drug Cisplatin

Zhonglie Yang, Li Lin, Xiaoyan Peng, Xinyi Yu, Xiaobin Zhang, Hezhong Jiang, and Jiahong Li*   

  1. School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan 614202, China
  • Received:2020-12-04 Revised:2021-01-30 Online:2021-01-20 Published:2021-01-20
  • Contact: *,Email: jiahongljh@163.com (J. L.)
  • Supported by:

Abstract: Since 1978, cisplatin has become a leading anticancer drug for its high efficacy and unique mechanism of action. As a representative of platinum anticancer drugs, cisplatin has an excellent curative effect and broad application range of cancer. However, its application is limited by high toxicity and drug resistance. This review mainly focuses on adverse reactions and drug resistance of cisplatin.


Key words: cisplatin, anticancer, adverse reaction, resistance

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