Cover Illustration
2018, Vol.2 No.4
The cover picture shows the subcellular distribution of DNA nanostructures in U87MG cells and inorganic gold nanoparticles being used as comparison. DNA origami nanostructures were distributed in early endosome, late endosome, lysosome, and eventually in late nucleosome and lysosome. Gold nanoparticles entered the cells from early endosome to late endosome, and then exited the cells through exocytosis. Compared with gold nanoparticles, DNA origami stays longer and more in organelles, which proves that it has better biocompatibility and low toxicity. More details are discussed in the article by Wang et al. on page 190100.