2022,6 (3-4)
The cover picture shows the progress of chemical composition, pharmacological effects and toxic side effects of A. catechu. More details are discussed in the article by Liu et al. on page 220004. The cover picture shows the progress of chemical composition, pharmacological effects and toxic side effects of A. catechu. More details are discussed in the article by Liu et al. on page 220004.
2022,6 (1-2)
The cover picture shows a persulfate-enhanced silver ion against SARS-CoV-2 with 99.54% of antiviral activity, evidencing its potential as an efficient and rapid alternative for controlling viral spread. More details are discussed in the article by Zhu et al. on page 210013. The cover picture shows a persulfate-enhanced silver ion against SARS-CoV-2 with 99.54% of antiviral activity, evidencing its potential as an efficient and rapid alternative for controlling viral spread. More details are discussed in the article by Zhu et al. on page 210013.
2021,5 (3-4)
The cover picture shows that Paeonia is composed of P. suffruticosa Andr, P. labiflora, P. delavayi, P. rockii, etc. Monopenoids have been isolated in the genus, which can be divided into paeoniflorin type paeonisufrrone type, albiflorin type, paeoniflorone type, and paeoniflorgenone type. More details are discussed in the article by Xu et al. on page 210011. The cover picture shows that Paeonia is composed of P. suffruticosa Andr, P. labiflora, P. delavayi, P. rockii, etc. Monopenoids have been isolated in the genus, which can be divided into paeoniflorin type paeonisufrrone type, albiflorin type, paeoniflorone type, and paeoniflorgenone type. More details are discussed in the article by Xu et al. on page 210011.
2021,5 (2)
The cover picture shows that L-OHP induced
T-ALLs cells death by blocking the PI3K/Akt signaling pathway to inhibit cell
proliferation, increase intracellular calcium concentration and cellular
promote ROS-mediated mitochondrial-dependent apoptosis.More details are
discussed in the article by Cheng et al. on page 210003.
The cover picture shows that L-OHP induced T-ALLs cells death by blocking the PI3K/Akt signaling pathway to inhibit cell proliferation, increase intracellular calcium concentration and cellular promote ROS-mediated mitochondrial-dependent apoptosis.More details are discussed in the article by Cheng et al. on page 210003.
2021,5 (1)
The cover picture shows computational drug design methods that have been applied for examining transient receptor potential ankyrin 1 (TRPA1) and its ligands. Three binding sites of ligands have been proposed for TRPA1 so far. The binding of various ligands into TRPA1 has been explored with molecular docking and molecular dynamics.More details are discussed in the article by Timonen et al. on page 200021. The cover picture shows computational drug design methods that have been applied for examining transient receptor potential ankyrin 1 (TRPA1) and its ligands. Three binding sites of ligands have been proposed for TRPA1 so far. The binding of various ligands into TRPA1 has been explored with molecular docking and molecular dynamics.More details are discussed in the article by Timonen et al. on page 200021.
2020,4 (4)
The cover picture shows an effective inhibitory of triptolide on ovarian cancer. The cell viability, cycle, invasion assay and in vivo experiments have been performed. The survival results show that triptolide can inhibit the proliferation of A2780 and Skov-3 cells by a dose-dependent manner, and it has a small effect on normal cell proliferation within a certain concentration. More details are discussed in the article by Li et al. on page 200017. The cover picture shows an effective inhibitory of triptolide on ovarian cancer. The cell viability, cycle, invasion assay and in vivo experiments have been performed. The survival results show that triptolide can inhibit the proliferation of A2780 and Skov-3 cells by a dose-dependent manner, and it has a small effect on normal cell proliferation within a certain concentration. More details are discussed in the article by Li et al. on page 200017.
2020,4 (3)
The cover picture shows EGFR signal transduction: when the extracellular domain binds to growth factors or other ligands, EGFR dimerization with other members of the family results in phosphorylation of tyrosine kinase and activating various signaling pathways downstream of EGFR, such as MAPK, PI3K/Akt and STAT, leading to gene transcription, cell cycle progression and apoptosis. In addition, the advances of small-molecule inhibitors on the target of EGFR include 4-anilinoquinazolines, “U-type” pyrimidines, thiophene [3,2-d] pyrimidines, oxyisoindoles and amino benzimidazoles. More details are discussed in the article by Zi et al. on page 200011.
2020,4 (1-2)
The cover picture shows chemical constituents and pharmacological effects of Citrus medica L. var. sarcodactylis Swingle. More details are discussed in the article by Jiang et al. on page 190014.
2019,3 (4)
The cover picture shows stilbenoids from Leguminosae and their bioactivities. More details are discussed in the article by Zhang et al. on page 200004.
2019,3 (3)
The cover picture shows an overview on the structure and properties of chitosan. More details are discussed in the article by Wu et al. on page 190013.
2019,3 (2)
The cover picture shows an overview of flavonoids and triterpenoids in Broussonetia papyrifera and their biological activities. More details are discussed in the article by Li et al. on page 190004.
The cover picture shows an overview of flavonoids and triterpenoids in Broussonetia papyrifera and their biological activities. More details are discussed in the article by Li et al. on page 190004.
2019,3 (1)
The cover picture shows an overview of triterpenes in the genus Ficus and their various bioactivities. More details are discussed in the article by Wang et al. on page 190004. The cover picture shows an overview of triterpenes in the genus Ficus and their various bioactivities. More details are discussed in the article by Wang et al. on page 190004.
2018,2 (4)
The cover picture shows the subcellular distribution of DNA nanostructures in U87MG cells and inorganic gold nanoparticles being used as comparison. DNA origami nanostructures were distributed in early endosome, late endosome, lysosome, and eventually in late nucleosome and lysosome. Gold nanoparticles entered the cells from early endosome to late endosome, and then exited the cells through exocytosis. Compared with gold nanoparticles, DNA origami stays longer and more in organelles, which proves that it has better biocompatibility and low toxicity. More details are discussed in the article by Wang et al. on page 190100.
2018,2 (3)
The cover picture shows the common mycotoxins and marine biotoxins in foods. More details are discussed in the article by Ou et al. on page 180011.
The cover picture shows the common mycotoxins and marine biotoxins in foods. More details are discussed in the article by Ou et al. on page 180011.
2018,2 (2)
The progress in structures of polyketides isolated from marine sponge-associated was summarized. More details are discussed in the article by Wu et al. on page 180006.
The progress in structures of polyketides isolated from marine sponge-associated was summarized. More details are discussed in the article by Wu et al. on page 180006.
2018,2 (1)
The cover picture shows the forms and structures of phlorotannins in different brown algae. The progress in bioactivities of phlorotannins was summarized. More details are discussed in the article by Wu et al. on page 180001. The cover picture shows the forms and structures of phlorotannins in different brown algae. The progress in bioactivities of phlorotannins was summarized. More details are discussed in the article by Wu et al. on page 180001.
